Abstract: The intensive and large-scale development of livestock and poultry breeding industry has resulted in a sharp increase of livestock manure. Meanwhile, improper treatment of livestock manure could pollute the surrounding soil, water and air, which is one of the main sources of agriculture non-point source pollution in China. We conducted a bibliometric analysis based on the core collection database of the Web of Science, using the CiteSpace knowledge map analysis tool, VOSviewer visual analysis software and HistCite citation analysis tool to count the number of publications and their distributions in disciplines, contributor countries (regions) and institutions, publish journals and hotspots and trends in the field of returning biogas slurry to cropland. ① Research in this field has attracted increasing attention worldwide between 2000 to 2021, and the top 3 categories of the publications are soil science, environmental sciences and agronomy. ② The United States, China, Germany, Australia and France are the major contributors of academic articles in this field, and have established close cooperation relationships with each other. ③ “Agriculture Ecosystems & Environment”, “Geoderma” and “Science of the Total Environment” are the top 3 publishing journals in the field of returning biogas slurry to cropland. Besides, “Science of the Total Environment”, “Geoderma”, “Agriculture Ecosystems & Environment”, and “Catena” are the main journals that have high impacts (one year). ④The future research trend in this field will focus mainly on the mechanism of biogas slurry microbes to promote soil fertility, and exploration of suppression mechanism to prevent and control soil-borne diseases. This paper is based on bibliometric data of the researches in the field of returning biogas slurry to cropland between 2000-2021. Soil fertility, organic matter, crop yield, inhibition of pathogenic microorganism become the current hotspots of biogas slurry utilization. With the continuous development of the high-throughput sequencing technology, the knowledge of soil microbial communities has been greatly expanded. Returning biogas slurry to cropland can not only turn the manure waste into treasure macroscopically, but also can antagonize soil-borne pathogens to protect soil micro-ecological health microscopically. These results are useful for returning biogas slurry to develop a greener and effective agriculture in the future.