Abstract: Microbial residue is an important contributor to soil organic carbon pool. In order to clarify the effects of exogenous nitrogen (N) addition on the accumulation dynamics of soil microbial residues, 122 groups of experimental observation data were collected from literatures published from 1980 to 2020. Meta-analysis method was used to analyze the effects of exogenous N addition on the accumulation dynamics of soil microbial residues, with amino sugars as the target component of microbial residues. The effects of quantity and type of N addition on the accumulation quantity and composition ratio of residues from different microbial sources in soil were analyzed quantitatively, and the main influencing factors were analyzed systematically. The results of integrated analysis showed that the addition of exogenous N (0 ~ 6000 kg hm⁻¹) significantly promoted the accumulation of microbial residues, and caused a significant change in the relative proportion of fungal and bacterial residues in the soil. Compared with the control without N source, the contents of total amino sugars in soil increased by 27%, among which the contents of glucosamine, galactosamine and muramic acid increased by 22.5%, 29.8% and 19.0%, respectively. The effects of different kinds of exogenous N on the accumulation characteristics of amino sugar were also different, which showed that the addition of organic N (such as animal manure) promoted the accumulation of amino sugars more than that of inorganic N. In addition, the effect of N addition on amino sugar was also closely related to environmental factors such as soil C/N ratio, land use type and natural rainfall. Whether carbon source is added or not had a great impact on the response of microbial residues, which was shown as follows: the addition of carbon source did not reduce the response of soil glucosamine and muramic acid to N addition, and weakened the contribution proportion of microbial residues to soil organic matter; Under the condition of N source combined with carbon source, the accumulation of soil amino sugar was significantly higher than that of single N source. This indicates that there is a carbon-nitrogen coupling effect on the accumulation of microbial residues.